What's the difference between RT-PCR and PCR test? Atlys Customer Delight December 24, 2021 02:52 Updated In short - none. RT-PCR and PCR have almost the same levels of significance, and either one is accepted. You can learn more about how does the test work technically here. Related articles When should I get tested for COVID-19 to come back to the United States? Is Atlys safe? Comments 0 comments Please sign in to leave a comment.